• 更新时间: 2016-07-15 11:07:53
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Tools to analyse bisulfite-converted reads.

Cytosine methylation is probably the best-studied form of epigenetic regulation of gene expression. The Bisulfite Sequencing plugin offers an all-in-one solution to common problems that scientists face when studying cytosine methylation data:

  • The plugin reveals methylated cytosines genome wide and at single base level resolution.

  • Users can compare cytosine methylation between samples and identify genomic regions where methylation levels differ

  • Support for reduced representation sequencing. The analysis can be focused on targeted regions expected to methylated.

  • Included statistical tools allow sample comparison and accommodate different experimental designs. Results are easy-to-interpret and exportable.

  • All functionalities required for comprehensive bisulfite sequencing analysis are split into three user friendly tools, which can combined into an automated workflow.