Cytosine methylation is probably the best-studied form of epigenetic regulation of gene expression. The Bisulfite Sequencing plugin offers an all-in-one solution to common problems that scientists face when studying cytosine methylation data:
The plugin reveals methylated cytosines genome wide and at single base level resolution.
Users can compare cytosine methylation between samples and identify genomic regions where methylation levels differ
Support for reduced representation sequencing. The analysis can be focused on targeted regions expected to methylated.
Included statistical tools allow sample comparison and accommodate different experimental designs. Results are easy-to-interpret and exportable.
All functionalities required for comprehensive bisulfite sequencing analysis are split into three user friendly tools, which can combined into an automated workflow.